Compile Data Set for Download or QSAR
Found 26 of ki data for complexid = 50000178
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50049757(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)copy SMILEScopy InChI
Affinity DataKi:  0.0350nMAssay Description:Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ65JWPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50162983(6-[5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-3-yl]...)copy SMILEScopy InChI
Affinity DataKi:  0.230nMAssay Description:Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ65JWPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50135594((+/-)-2-(6-chloropyridin-3-yl)-9-aza-bicyclo[4.2.1...)copy SMILEScopy InChI
Affinity DataKi:  6.5nMAssay Description:Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50162988(3-[5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridin...)copy SMILEScopy InChI
Affinity DataKi:  7.10nMAssay Description:Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ65JWPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50049756(3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridine |...)copy SMILEScopy InChI
Affinity DataKi:  7.70nMAssay Description:Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ65JWPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50162986(3-Ethynyl-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-...)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ65JWPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50097613(3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-phenylet...)copy SMILEScopy InChI
Affinity DataKi:  8.60nMAssay Description:Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ65JWPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50162987(6-[5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridin...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ65JWPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50162984(3-(6-Fluoro-hex-1-ynyl)-5-((S)-1-methyl-pyrrolidin...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ65JWPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50162982(3-Hex-1-ynyl-5-((S)-1-methyl-pyrrolidin-2-ylmethox...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ65JWPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50162985(2-Methyl-4-[5-((S)-1-methyl-pyrrolidin-2-ylmethoxy...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ65JWPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50135597(2-Pyridin-3-yl-9-aza-bicyclo[4.2.1]non-2-ene | CHE...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Displacement of [3H]epibatidine from alpha3beta2 nAChR after 4 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)copy SMILEScopy InChI
Affinity DataKi:  47nMAssay Description:Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50162989(10-[5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridi...)copy SMILEScopy InChI
Affinity DataKi:  48nMAssay Description:Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ65JWPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50135595(2-(6-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi:  56nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50135592(2-(5-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi:  468nMAssay Description:Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50006615(CHEMBL3235483)copy SMILEScopy InChI
Affinity DataKi:  678nMAssay Description:Displacement of [3H]epibatidine from alpha3beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3215RPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50006612(CHEMBL3235488)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3215RPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50006613(CHEMBL3235480)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3215RPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50135593(2-(4-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi:  1.99E+3nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50006616(CHEMBL3235484)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3215RPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50006614(CHEMBL3235482)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3215RPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50326197(1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...)copy SMILEScopy InChI
Affinity DataKi:  4.20E+3nMAssay Description:Binding affinity to nicotinic alpha3beta2 receptor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4BS7PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50400739(CHEMBL2203550)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from alpha3beta2 nAChR after 4 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66WSPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50135596(2-(2-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed